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Cages were equally split between SJL and albino C57BL/6 strains and group sizes of 3 or 5 ( N = 24). Discriminant validity with open field measures was assessed to determine if tube test scores are independent of anxiety. This study assessed the convergent validity of three dominance correlates (urinary darcin, tube test score, preputial gland to body length ratio) with wound severity and rankings based on home cage behavior, using factor analysis. Several correlates of dominance status have been identified, but none have been directly compared to home cage behavior in standard housing. Unfortunately, dominance rank is often not assessed because of time intensive observations or tests. Aggression within a group is typically displayed by the dominant mouse targeting lower ranking subordinates thus, the strategies for preventing aggression may be more successful if applied specifically to the dominant mouse.
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3United States Department of Agriculture, Agricultural Research Service, Livestock Behavior Research Unit, Purdue University, West Lafayette, IN, United StatesĪggression among group housed male mice continues to challenge laboratory animal researchers because mitigation strategies are generally applied at the cage level without a good understanding of how it affects the dominance hierarchy.2Department of Biological Sciences, Purdue University, West Lafayette, IN, United States.1Department of Animal Science, Purdue University, West Lafayette, IN, United States.Erasmus 1, Heng-Wei Cheng 3 and Brianna N.